Here is the answer to The enzyme that can replicate DNA is called ______.
The enzyme that can replicate DNA is called ______.
- Below are the answer and explanations.
DNA polymerase, also known as DNA-dependent DNA polymerase, is a class of enzymes that uses parental DNA as a template to catalyze the polymerization of substrate dNTP molecules to form daughter DNA.
This enzyme was first discovered by American scientist Arthur Komberg in 1957 in E. coli and was called DNA polymerase Ⅰ (DNA polymerase Ⅰ, abbreviated as pol Ⅰ) Later, a variety of DNA polymerases were found in other prokaryotes and eukaryotes.
The common features of these DNA polymerases are.
1) have 5’→3′ polymerase activity, which determines that DNA can only be synthesized along the 5’→3′ direction.
2) requires a primer, DNA polymerase cannot catalyze the de novo synthesis of DNA strands, but only the addition of dNTP to the 3′-OH end of the nucleotide strand. Thus, the beginning of replication requires a segment of DNA primer at the 3′-OH end as the starting point to synthesize a new strand in the 5’→3′ direction.
There are several types of DNA polymerases, and there are three types of E.coli. Usually, DNA polymerases have the following common characteristics.
1) require a DNA template, hence these enzymes are also called DNA-dependent DNA polymerases.
2) require RNA or DNA as a primer (primer), i.e., DNA polymerases cannot catalyze ab initio.
3) catalyze the addition of dNTP to the 3′-OH terminus of the primer at a rate of 1000 nt/min, and thus DNA synthesis is oriented from 5′ to 3′
4) All three DNA polymerases are multifunctional enzymes, which function at different stages of the DNA replication and repair process.
Here is the correct answer to The enzyme that can replicate DNA is called ______.
- DNA polymerase
The enzyme that can replicate DNA is called DNA polymerase.
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